Thứ Hai, 17 tháng 5, 2010

Viral Infections of the Mouth (cont 2)

Human Papillomavirus

Background

HPVs are members of the Papovaviridae family, which are small icosahedral viruses that contain circular DNA. The term papova is derived from the first 2 letters of their common clinical features, as follows: papillomatous lesions, polyomas (varied tumor induction), and vacuolization of infected cells.

At least 106 types of HPV have been discovered. The infectivity of HPV is incompletely understood. Some types of HPV may act in concert with cofactors such as diminished immunity or sun exposure.

Although the magnitude of its risk is not completely clear, HPV is currently considered to be an independent risk factor for the development of oral squamous cell carcinoma, especially in younger cancer patients and persons with tonsillar carcinoma. Odds ratios range in various studies from 2.0 to 5.4, and variation is in part associated with the method of viral detection. Certain HPV types have been more strongly associated with malignancies of the tonsils, anus, genital tract, and other areas.

Pathophysiology

HPV is a 50-nm virus composed of double-stranded DNA with no envelope. The virus penetrates the mucosal epithelium and invades the cells of the basal layer, where the viral circular DNA inserts into the host DNA.

Frequency

HPV has been detected in the oral cavity of approximately 6-10% of children and adolescents. The rate of HPV in the oral cavity of healthy adults is estimated at 5-80%. Persistent oral HPV infection in one spouse appears to predict similar infection in the other spouse, regardless of oral sex habits.21

HPV-16 has been linked to the development of dysplasia and carcinoma of the uterine cervix. Oral HPV-16 detection is more common in women with HPV-associated cervical dysplasia.22 Oral HPV-16 detection is much less common in children than in adolescents and adults. However, persistence of HPV-16 and other high-risk HPV types is more common in infants of parents with persistent oral HPV infections and high-risk behaviors.

Oral HPV may also be more common in renal dialysis patients. HPV lesions are more common in immunocompromised patients, especially in HIV-infected patients and in solid organ transplant recipients.23,24 The recent development of effective preventative HPV vaccines may, in the future, have a significant impact on these rates.25,26

Mortality/morbidity

Most oral lesions caused by HPV are benign. Lesions are usually painless and not ulcerated, although they may be secondarily ulcerated by trauma. Lesions may be more common and severe in immunocompromised patients than in other patients.

Clinical history

Verruca vulgaris, or common warts (HPV-2; HPV-4; occasionally HPV-1, HPV-3, HPV-27, HPV-29, and HPV-57), are more common on the skin than in the oral cavity. On the oral mucosa, the warts are usually sessile, verrucous, and white; solitary or multiple; and elevated with discrete borders. The lesions most commonly occur on the lips, hard palate, or gingiva. Verruca plana is similar but less elevated. Warts are commonly observed on the digits of patients with oral infection.

Condyloma acuminata, or genital warts (HPV-6, HPV-11), may also affect the oral mucosa. These lesions are usually cerebriform, pink, and sessile and solitary or multiple; they occur more commonly on nonkeratinized mucosa than on keratinized mucosa. Patients infected with HPV-6 or HPV-11 and their sexual partners may have genital lesions, and the lesions have presumably been spread to the oral cavity via oral-genital contact.

Focal epithelial hyperplasia, or Heck disease (HPV-13, HPV-32), may appear as an epidemic in young adults in small communities. This condition was first described in native North American people. Heck disease typically manifests as multiple, smooth, sessile nodules, often on the mucosal surface of the lower lip or on the buccal mucosa. Lesions may regress spontaneously after several months.

HPV may have a role in oral premalignancy and malignancy in humans.27,28 HPV-16 in particular (but also HPV-18, HPV-33, HPV-35, and others) have been associated with verruciform proliferations in the oral cavity, oral premalignant lesions, and oral squamous cell carcinoma.29,30,31,32 HPVs may interfere with the normal function of regulatory proteins, such as p53, p16, and pRb, and they may have a promoter effect.

Human papillomavirus (HPV). Verruca vulgaris on t...

Human papillomavirus (HPV). Verruca vulgaris on the lateral border of the tongue exhibits the multiple, sharp-tipped, white, verrucous appearance, which is classic for this lesion in the oral cavity. Not all verrucae are so clinically diagnostic. Courtesy of Rose Yin Geist, DDS.

Human papillomavirus (HPV).  Verruca vulgaris on t...

Human papillomavirus (HPV). Verruca vulgaris on the lateral border of the tongue exhibits the multiple, sharp-tipped, white, verrucous appearance, which is classic for this lesion in the oral cavity. Not all verrucae are so clinically diagnostic. Courtesy of Rose Yin Geist, DDS.


Human papillomavirus (HPV). This verruca on the r...

Human papillomavirus (HPV). This verruca on the retromolar pad shows much less keratinization and a broader base. Verrucae and papillomas may be difficult to differentiate, but both are usually surgically excised.

Human papillomavirus (HPV). This  verruca on the r...

Human papillomavirus (HPV). This verruca on the retromolar pad shows much less keratinization and a broader base. Verrucae and papillomas may be difficult to differentiate, but both are usually surgically excised.


This is a verruca vulgaris of the anterior maxill...

This is a verruca vulgaris of the anterior maxillary gingiva in a healthy young male. He had recently resolved a wart on his finger.

This is a verruca vulgaris of  the anterior maxill...

This is a verruca vulgaris of the anterior maxillary gingiva in a healthy young male. He had recently resolved a wart on his finger.


Papillomas, which are of questionable viral origi...

Papillomas, which are of questionable viral origin, are frequent findings in the oral cavity, especially on the lateral/ventral tongue and soft palate.

Papillomas, which are of  questionable viral origi...

Papillomas, which are of questionable viral origin, are frequent findings in the oral cavity, especially on the lateral/ventral tongue and soft palate.


These small papillomas on the lateral tongue of a...

These small papillomas on the lateral tongue of a young woman showed histologic evidence of HPV in the form of extensive koilocytosis.

These small papillomas on the  lateral tongue of a...

These small papillomas on the lateral tongue of a young woman showed histologic evidence of HPV in the form of extensive koilocytosis.


Multiple condylomas are seen in this HIV+ male wi...

Multiple condylomas are seen in this HIV+ male with a CD4 count of 11, and recent neurosyphilis.

Multiple condylomas are seen in  this HIV+ male wi...

Multiple condylomas are seen in this HIV+ male with a CD4 count of 11, and recent neurosyphilis.


Human papillomavirus (HPV). Condyloma acuminatum ...

Human papillomavirus (HPV). Condyloma acuminatum of the oral cavity usually appears as a pinker, more cerebriform lesion (as shown here) compared with the whiter, more verrucous appearance of verruca vulgaris. Courtesy of A.K. ElGeneidy, DDS.

Human papillomavirus (HPV).  Condyloma acuminatum ...

Human papillomavirus (HPV). Condyloma acuminatum of the oral cavity usually appears as a pinker, more cerebriform lesion (as shown here) compared with the whiter, more verrucous appearance of verruca vulgaris. Courtesy of A.K. ElGeneidy, DDS.


Human papillomavirus (HPV). Some patients with co...

Human papillomavirus (HPV). Some patients with condyloma acuminatum present with multiple oral lesions. Lesion on the lingual frenum occurred in the same man shown in Image 14. Courtesy of A.K. ElGeneidy, DDS.

Human papillomavirus (HPV). Some  patients with co...

Human papillomavirus (HPV). Some patients with condyloma acuminatum present with multiple oral lesions. Lesion on the lingual frenum occurred in the same man shown in Image 14. Courtesy of A.K. ElGeneidy, DDS.


Human papillomavirus (HPV). Condylomata on the lo...

Human papillomavirus (HPV). Condylomata on the lower lip, as well as other sites at the initial presentation (same patient as in Images 14-15). This presentation is unusually extensive. Multiple condylomata may be synchronous or metachronous. This patient did not present with genital condylomata; however, the appropriate health care practitioner should examine patients with condyloma to determine the extent of the disease. The source of infection (eg, a partner who is infected) should also be determined and treated. Courtesy of A.K. ElGeneidy, DDS.

Human papillomavirus (HPV).  Condylomata on the lo...

Human papillomavirus (HPV). Condylomata on the lower lip, as well as other sites at the initial presentation (same patient as in Images 14-15). This presentation is unusually extensive. Multiple condylomata may be synchronous or metachronous. This patient did not present with genital condylomata; however, the appropriate health care practitioner should examine patients with condyloma to determine the extent of the disease. The source of infection (eg, a partner who is infected) should also be determined and treated. Courtesy of A.K. ElGeneidy, DDS.


A mnemonic for remembering the microscopic and cl...

A mnemonic for remembering the microscopic and clinical shapes of verruciform oral lesions: Verruca vulgaris is shaped like a series of inverted V's. Condyloma acuminata are shaped like a series of C's placed on their sides. Papillomas are pedunculated like the letter P.

A mnemonic for remembering the  microscopic and cl...

A mnemonic for remembering the microscopic and clinical shapes of verruciform oral lesions: Verruca vulgaris is shaped like a series of inverted V's. Condyloma acuminata are shaped like a series of C's placed on their sides. Papillomas are pedunculated like the letter P.


Human papillomavirus (HPV). Heck disease in the b...

Human papillomavirus (HPV). Heck disease in the buccal mucosa of a 7-year-old boy. Courtesy of Sheldon Mintz, DDS.

Human papillomavirus (HPV). Heck  disease in the b...

Human papillomavirus (HPV). Heck disease in the buccal mucosa of a 7-year-old boy. Courtesy of Sheldon Mintz, DDS.


Differentials

Verruca vulgaris and condyloma acuminata

Papilloma

Focal epithelial hyperplasia

Verrucous Carcinoma

Proliferative verrucous leukoplakia

Squamous Cell Carcinoma

Focal epithelial hyperplasia

Focal fibrous hyperplasia (fibroma)

Condyloma acuminata

Papillomatosis

Condyloma plana

Verruca plana

Connective-tissue tumor

Salivary gland tumor

Workup

Laboratory studies

The typing of HPV, if deemed necessary, may be performed by immunohistochemical detection of HPV structural proteins. This analysis has a low sensitivity. Enzyme-linked immunosorbent assay and polymerase chain reaction DNA amplification are more sensitive techniques for HPV detection.

Procedures33

Diagnosis is usually achieved with biopsy results. Excisional biopsy is commonly performed, and it has a high success rate as a treatment of these lesions.

Carbon dioxide laser treatment is problematic because viral DNA has been detected in the laser plume.34 Such laser treatment is considered potentially infectious to surgical personnel. However, HPV DNA was absent in the laser plume of the Er:YAG laser in one study.35

Histologic findings

When the production of viral DNA and structural proteins begins, koilocytosis also develops, with dark shrunken nuclei and cytoplasmic vacuolization of infected cells.

Verruca vulgaris typically exhibits a verrucous epithelial proliferation with hyperkeratosis. Koilocytes are frequently noted in the upper stratum spinosum and stratum corneum.

Condyloma acuminata may exhibit acanthosis, vacuolated keratinocytes, a compacter stratum corneum, and parakeratosis.

Focal epithelial hyperplasia (Heck disease) exhibits acanthosis of the spinous layer and thickened, fused rete pegs. The epithelial cells may exhibit intracellular edema. Slight parakeratosis is usually present.

Human papillomavirus (HPV). Verrucae and papillom...

Human papillomavirus (HPV). Verrucae and papillomas appear as frondlike epithelial proliferations. Verrucae tend to be more keratinized with sharper projections than papillomas.

Human papillomavirus (HPV).  Verrucae and papillom...

Human papillomavirus (HPV). Verrucae and papillomas appear as frondlike epithelial proliferations. Verrucae tend to be more keratinized with sharper projections than papillomas.


Human papillomavirus (HPV). Condyloma acuminatum ...

Human papillomavirus (HPV). Condyloma acuminatum generally has a papillary architecture and may microscopically resemble verruca vulgaris and papilloma (hematoxylin and eosin stain, original magnification X10). Courtesy of AK ElGeneidy, DDS.

Human papillomavirus (HPV).  Condyloma acuminatum ...

Human papillomavirus (HPV). Condyloma acuminatum generally has a papillary architecture and may microscopically resemble verruca vulgaris and papilloma (hematoxylin and eosin stain, original magnification X10). Courtesy of AK ElGeneidy, DDS.


Human papillomavirus (HPV). Koilocytes in the upp...

Human papillomavirus (HPV). Koilocytes in the upper epithelium are a helpful, although not completely reliable, indication that a lesion is associated with human papillomavirus. Koilocytes display a dark small nucleus with clear cytoplasm (hematoxylin and eosin stain, original magnification X100). Courtesy of Sheldon Mintz, DDS.

Human papillomavirus (HPV).  Koilocytes in the upp...

Human papillomavirus (HPV). Koilocytes in the upper epithelium are a helpful, although not completely reliable, indication that a lesion is associated with human papillomavirus. Koilocytes display a dark small nucleus with clear cytoplasm (hematoxylin and eosin stain, original magnification X100). Courtesy of Sheldon Mintz, DDS.


Human papillomavirus (HPV). Condyloma acuminatum ...

Human papillomavirus (HPV). Condyloma acuminatum may show brisk mitotic activity, although oral condyloma acuminatum is not considered a premalignant lesion (hematoxylin and eosin stain, original magnification X40). Courtesy of A.K. ElGeneidy, DDS.

Human papillomavirus (HPV).  Condyloma acuminatum ...

Human papillomavirus (HPV). Condyloma acuminatum may show brisk mitotic activity, although oral condyloma acuminatum is not considered a premalignant lesion (hematoxylin and eosin stain, original magnification X40). Courtesy of A.K. ElGeneidy, DDS.


Medical care

Oral lesions are usually treated with excisional biopsy. After the lesions have been removed and the diagnosis is confirmed by biopsy results, they usually do not recur unless reinfection occurs. To prevent reinfection, the source of infection (eg, digits, lesions on sexual partners) should be determined and treated if possible. In HIV-infected patients, recurrence of the lesions is widely reported. The treatment objective can sometimes be limited to control rather than eradication of the HPV lesions. Reports have indicated that solid organ transplant recipients can also be at risk for recurrent and florid oral lesions, which also can limit the treatment objective to control rather than cure.

Topical agents are sometimes used. Cidofovir is an antiviral agent that is a nucleotide analog of deoxycytidine monophosphate. Cidofovir is approved for intravenous administration in patients with AIDS who have CMV retinitis. Topical administration of this medication (1% cream or gel) has been used for refractory condyloma acuminata and recurrent genital herpes. Cidofovir is occasionally used for oral lesions. When used systemically, it may cause nephrotoxicity, uveitis, and numerous other adverse effects.36

Intralesional injections may be used in refractory cases, but they are not recommended for the primary treatment of oral lesions. Bleomycin is a cytotoxic polypeptide that inhibits DNA synthesis in cells and viruses. Adverse effects include pain with injection, local urticaria, Raynaud phenomenon, and possible tissue necrosis. Bleomycin should be considered a third-line treatment when standard therapies have failed. IFN-A is a naturally occurring cytokine with antiviral, antibacterial, anticancer, and immunomodulatory effects. Intralesional administration of IFN-A is associated with mild flulike symptoms. Treatments may be required for several weeks to months before beneficial results are observed. IFN-A should be considered a third-line treatment to be used after standard therapies have failed. Research on topical low-dose IFN-A is being conducted. The results of this therapy have yet to be communicated.

Systemic agents, such as retinoids or synthetic vitamin A analogs, may be used to treat extensive lesions in patients who are immunocompromised or immunosuppressed. They may be used in conjunction with other treatments. Adverse effects may include liver function abnormalities, increased serum lipid levels, and teratogenicity. Some clinicians have used podophyllin, but it is not approved by the FDA for this purpose.

Imiquimod 5%(Aldara), a toll-like receptor 7 activator, has been approved for external genital warts and has been tried with varied success in the oral cavity.

The long-term effect of preventive HPV vaccination on oral HPV-related disease is not yet known but offers potential hope that vaccination prior to exposure to HPV may result in a decrease in the incidence of HPV-related oral lesions. Cross-reactivity of the immune response to the HPV subtypes targeted by the vaccines may render the vaccines useful to prevent oral lesions associated with HPV.

Medication

See Medication.

Follow-up

Further outpatient care

Monitor the patient for the recurrence of the condition.

Consult a dermatologist for patients with skin lesions.

Consult an obstetrician/gynecologist (for females) or a urologist (for males) for patients with condyloma acuminata (and their sexual partners) to detect, diagnose, and treat any coexistent lesions of the anogenital lesion, which may be premalignant.

If the initial therapy is inadequate or lesions recur, evaluation of the patient for underlying immunosuppression may be warranted.

Complications

Local scarring from surgical excision may occur.

Transmission to family members or sexual partners is possible.

Recurrence may be observed.

Prognosis

The prognosis is excellent. In extreme conditions, the treatment objective is limited to control rather than eradication of the HPV lesions.

Education

Educate the patient concerning the etiology and the route of transmission to prevent reinfection.

Medical/legal pitfalls

  • Failure to refer patients for evaluations of potentially malignant anogenital lesions
  • Failure to diagnose or misdiagnosis of a verrucous carcinoma
  • Failure to inform patients about the rare risk of oral malignancy if inadequately diagnosed and treated
  • Failure to indicate the need for follow-up, even after treatment
  • Failure to warn patients of the risk of recurrence or of treatment failure
  • Failure to indicate treatment availability
  • Failure to inform patients of the risk of transmission of HPV
  • Failure to inform patients with condyloma of the need to treat sexual partners
  • Failure to search for immunosuppression in patients with treatment failures and lesion recurrences

70 nhận xét:

  1. Hi there, I am a big fan of your site, and would like to share one more about verruca vulgaris and treatment.

    Verruca Vulgaris

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    1. i am so glad to write this article today to tell the world how Chief Dr Lucky cured my HPV virus that have been in my body since five years ago, ever since then my life has been in complete,i have used so many drugs that was prescribed to me by several doctors,but it didn't cure my HPV VIRUS neither did it reduce the pain, i was checking for solution on the internet then miraculously came across Chief Dr Lucky the powerful herbalist that cure HPV INFECTION,then i contacted his email, i explained everything to him and he prepared a herbal cure and send it to me that was how i got cured from HPV disease totally after receiving his herbal medicine, so my friends viewers why waiting and be suffering with this HPV virus when there is someone like Chief Dr Lucky that can cure any disease HIV/ CANCER/ HEPATITIS C VIRUS,HERPES VIRUS,ALS VIRUS. you can contact his via email: chiefdrlucky@gmail.com .Whats App or call +2349065398067

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    6. Hi, I am Patrice cythia, from Houston, Texas, USA. I was living with HPV(human papilloma virus) for almost 2 years, i was not myself, my body was always inching with pains until i was on the internet searching for a remedy. So luckily, i was reading testimonials of clients who was cured of herpes by the amazing spell caster named Dr idedia, an ancient spell doctor from West Africa.I contacted him by email, and within 15 minutes he got back to me and ask of my details which i provide to him, he consulted his oracle and told me the solution to my problem and how to go about it, i did is he told me and about the two days i got the cure which he prepared and send to me through DHL service, i took the cure as instructed by him getting to two days i was cured, my HPV(human papilloma virus) was cured up. All thanks to the superb healing herbs of Dr idedia.
      You too can get in contact with him today if you wanna be cured from HPV(human papilloma virus) you having by
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  7. Treatment for Pemphigus includes Coconut Oil, Vitamin coconut oil contain fatty acids which significantly reduce inflammation throughout the body.

    Trả lờiXóa
  8. i am so glad to write this article today to tell the world how Dr omohan cured my HPV virus that have been in my body since five years ago, ever since then my life has been in complete,i have used so many drugs that was prescribed to me by several doctors,but it didn't cure my HPV VIRUS neither did it reduce the pain, i was checking for solution on the internet then miraculously came across Dr omohan the powerful herbalist that cure HPV INFECTION,then i contacted his email, i explained everything to him and he prepared a herbal cure and send it to me that was how i got cured from HPV disease totally after receiving his herbal medicine, so my friends viewers why waiting and be suffering with this HPV virus when there is someone like Dr omohan that can cure any disease HIV/ CANCER/ HEPATITIS C VIRUS,HERPES VIRUS,ALS VIRUS. you can contact his via: email dromohanherbalmedicine@gmail com .whatsapp or call +2348164816038

    Trả lờiXóa
    Trả lời
    1. Hello viewers all over the globe I am Caroline from USA, I have been suffering from HPV virus for the past 2 years now, I have went to several hospitals taking different treatment from doctors but still yet no improvement, I have done research on internet seen different testimony how some people get cured but I don’t believe does testimony again because of what happened to me I have contacted so many doctors online, they all ask for is money I was scammed by 3 different doctors over $2000 still yet I was not cured so I tell a friend of mine about my problem she tells me to contact dr oso that his very good in healing people with his medicine that she was cured from herpes by this some Dr oso I don’t believe her on thing she showed me her results on how was cured she gives me his Email few weeks later I contacted him and tell him about my problem he tell me not to be worried that his going to prepare the medicine and send to me through EMS delivery so after some days I received the medicine and I was take it as he Instructed me few weeks later I go for check up to no if I’m finally cured, could you believe me when the results come out I was negative I jump up I was very happy. Please my dear friends if you have any kind of diseases or virus please contact Drosohaberhome@gmail.com/ dr.osoherberhome1@outlook.com or WhatsApp +2348162084839. you can email me to for more info about dr oso . toddcaroline79@gmail.com. Thank you so much Dr oso I’m forever great full please my dear friends don’t believe on does comment online they all fake doctors. only Dr oso I see real. Please beware of scammers...

      Xóa
  9. Hello viewers all over the globe I am caroline from USA, I have been suffering from HPV virus for the past 2 years now, I have went to several hospitals taking different treatment from doctors but still yet no improvement, I have done research on internet seen different testimony how some people get cured but I don’t believe does testimony again because of what happened to me I have contacted so many doctors online, they all ask for is money I was scammed by 3 different doctors over $2000 still yet I was not cured so I tell a friend of mine about my problem she tells me to contact dr oso that his very good in healing people with his medicine that she was cured from herpes by this some Dr oso I don’t believe her on thing she showed me her results on how was cured she gives me his Email few weeks later I contacted him and tell him about my problem he tell me not to be worried that his going to prepare the medicine and send to me through EMS delivery so after some days I received the medicine and I was take it as he Instructed me few weeks later I go for check up to no if I’m finally cured, could you believe me when the results come out I was negative I jump up I was very happy. Please my dear friends if you have any kind of diseases or virus please contact Drosohaberhome@gmail.com/ dr.osoherberhome1@outlook.com or WhatsApp +2348162084839. you can email me to for more info about dr oso . toddcaroline79@gmail.com. Thank you so much Dr oso I’m forever great full please my dear friends don’t believe on does comment online they all fake doctors. only Dr oso I see real. Please beware of scammers..

    Trả lờiXóa
  10. GOOD NEWS
    I don't just know the reason why some people is finding it difficult to believe that there is a cure for HPV, I have been suffering from HPV since last three years with my boyfriend but today I am happy that am cure from it with the herbal medicine of Dr JAJA the great healer,I was browsing the internet searching for help when I came across a testimony shared by someone on how Dr JAJ cure his HPV I was so much in need of getting his treatment but after all Dr JAJ brought a smile to my face with his herbal medicine. I am so much happy today that i have someone like this great healer out there, so my people out there kindly contact this great healer on his email address:drjajspellhome@gmail.com please sir keep your good work cause there are people out there who is in need of your healing medicine.once more contact him now: drjajspellhome@gmail.com you can call him or whatsApp his number +2349031670905

    Trả lờiXóa
  11. i am so glad to write this article today to tell the world how Chief Dr Lucky cured my HPV virus that have been in my body since five years ago, ever since then my life has been in complete,i have used so many drugs that was prescribed to me by several doctors,but it didn't cure my HPV VIRUS neither did it reduce the pain, i was checking for solution on the internet then miraculously came across Chief Dr Lucky the powerful herbalist that cure HPV INFECTION,then i contacted his email, i explained everything to him and he prepared a herbal cure and send it to me that was how i got cured from HPV disease totally after receiving his herbal medicine, so my friends viewers why waiting and be suffering with this HPV virus when there is someone like Chief Dr Lucky that can cure any disease HIV/ CANCER/ HEPATITIS C VIRUS,HERPES VIRUS,ALS VIRUS. you can contact his via email: chiefdrlucky@gmail.com .Whats App or call +2349065398067

    Trả lờiXóa
  12. i am so glad to write this article today to tell the world how Dr omohan cured my HPV virus that have been in my body since five years ago, ever since then my life has been in complete,i have used so many drugs that was prescribed to me by several doctors,but it didn't cure my HPV VIRUS neither did it reduce the pain, i was checking for solution on the internet then miraculously came across Dr omohan the powerful herbalist that cure HPV INFECTION,then i contacted his email, i explained everything to him and he prepared a herbal cure and send it to me that was how i got cured from HPV disease totally after receiving his herbal medicine, so my friends viewers why waiting and be suffering with this HPV virus when there is someone like Dr omohan that can cure any disease HIV/ CANCER/ HEPATITIS C VIRUS,HERPES VIRUS,ALS VIRUS. you can contact his via: email dromohanherbalmedicine@gmail com .whatsapp or call +2348164816038

    Trả lờiXóa
  13. i want to share to the whole world on how Dr muthuka
    help my Mother cure HPV Please help me
    thank Dr muthuka for his good work I really believe
    Genital Warts is known not to have a cure, my mother
    contacted this disease in 2017, i have done all my
    best to get cured from this disease but all to no
    avail until I go on search on internet then we get some testimony of Adams Tracy and some other people about how doctor
    muthuka herbal home on the internet who helps
    people cure any kind of diseases including HIV
    Cancer, Herpes etc, at first i doubted if it was real
    but decided to give it a try, when i contacted this
    herbal doctor he helped me with his herbal
    medicine and my mom was healed within (13days) and i
    went for a medical checkup and my doctor
    confirm it that my mother is now HPV negative.Contact this
    grate herbal doctor for any kind of disease or
    ailment via this email muthukaherbalhome@gmail.com
    or call him +2348034056542 or call +2348105817441 God we Bless You
    http://muhuka.blogspot.com
    .

    Trả lờiXóa
  14. I has suffered for Human papillomavirus HPV) for 2years, I was given some tablets at the hospital but I refused to take it, They said I have to be on it for life so I don't want take a drugs everyday for life. No point in taking medicine everyday when u won't get cure from it and I was advice to seek for natural herbal cure, after some time I found dr ODUWA is the most trustful herbalist that have herbs to cure wicked symptom’s, I emailed dr ODUWA, for 2weeks been his patient he cured my (HPV) with his herbal. I only used his natural herbs for two weeks it was 100% cure. I'm not (HPV) patient anymore. I'm happy about it i finally got cured out of this mess been in my body for 2years. I also recommend you if you're living with (HPV) or herpes symptoms i also want you to be free contact dr ODUWA with the email attach to my post. Dr.oduwaspellhome@gmail.com

    Trả lờiXóa

  15. I was in trouble when my doctor told me that i have been diagnosed with
    herpes and i know my family will face a serious problem . when i am gone i
    lost hope and wept most of the time, but one day i was surfing the internet
    i saw Dr. omohan herbal home contact number online i called him and he
    guided me. i asked him for solutions and he started the remedy for my
    health thank God,now everything is fine i am cured by Dr. omohan herbal
    medicine am very thankful to Dr. omohan and very happy with my hobby and
    family email him on (dromohanherbalmedicine@gmail.com) call/whatsapp number +2348164816038

    He can as well cure the following disease;

    Herpes,
    Asthma,
    Cancer,
    HSV1, &
    HSV2,
    Hepatitis B,
    HIV/AID ETC.

    Trả lờiXóa
  16. I know this may not be important to some of you here but most of you can benefit from this. Email>> Priestazibasolutioncenter@gmail.com
    I got an article about the cure and supplement on how i can get rid of Wart Virus, which i followed the tips and it has been really helpful to me since i started using it, and i guess some of you will need this as well so i will write down the Doctor number who gave me the cure to Get rid of WART Virus, i appreciate his effort and kindness so i am writing this here for anyone with similar problem to contact Dr Aziba for cure to any kind of disease such as DIABETICS,INFERTILITY CASES,FIBROID,HIV-AIDS,STD,HYPERTENSION,WEAK ERECTION, ARTHRITIS, HEPATITIS B ,STAPH INFECTION,ALS, HSV,HERPES,HAV,HCV, RELATIONSHIP ISSUES CANCER etc..just make your complain to him and he will surely help you.Remember a problem shared is a problem solved. Dr whats-App : [ +2348100368288 ] Dr Email: PRIESTAZIBASOLUTIONCENTER@GMAIL.COM





    I know this may not be important to some of you here but most of you can benefit from this. Email>> Priestazibasolutioncenter@gmail.com
    I got an article about the cure and supplement on how i can get rid of Wart Virus, which i followed the tips and it has been really helpful to me since i started using it, and i guess some of you will need this as well so i will write down the Doctor number who gave me the cure to Get rid of WART Virus, i appreciate his effort and kindness so i am writing this here for anyone with similar problem to contact Dr Aziba for cure to any kind of disease such as DIABETICS,INFERTILITY CASES,FIBROID,HIV-AIDS,STD,HYPERTENSION,WEAK ERECTION, ARTHRITIS, HEPATITIS B ,STAPH INFECTION,ALS, HSV,HERPES,HAV,HCV, RELATIONSHIP ISSUES CANCER etc..just make your complain to him and he will surely help you.Remember a problem shared is a problem solved. Dr whats-App : [ +2348100368288 ] Dr Email: PRIESTAZIBASOLUTIONCENTER@GMAIL.COM

    Trả lờiXóa

  17. I was in trouble when my doctor told me that i have been diagnosed with
    herpes and i know my family will face a serious problem . when i am gone i
    lost hope and wept most of the time, but one day i was surfing the internet
    i saw Dr. omohan herbal home contact number online i called him and he
    guided me. i asked him for solutions and he started the remedy for my
    health thank God,now everything is fine i am cured by Dr. omohan herbal
    medicine am very thankful to Dr. omohan and very happy with my hobby and
    family email him on (dromohanherbalmedicine@gmail.com) call/whatsapp number +2348164816038

    He can as well cure the following disease;

    Herpes,
    Asthma,
    Cancer,
    HSV1, &
    HSV2,
    Hepatitis B,
    HIV/AID ETC.

    Trả lờiXóa
  18. Hiv disease for the last 3 years and had pain hard to eat and cough are nightmares,especially the first year At this stage, the immune system is severely weakened, and the risk of contracting opportunistic infections is much greater. However, not everyone with HIV will go on to develop AIDS. The earlier you receive treatment, the better your outcome will be.I started taking ARV to avoid early death but I had faith in God that i would be healed someday.As a Hiv patent we are advise to be taking antiretroviral treatments to reduce our chance of transmitting the virus to others , few weeks ago i came on search on the internet if i could get any information on Hiv treatment with herbal medicine, on my search i saw a testimony of someone who has been healed from Hiv her name was Achima Abelard and other Herpes Virus patent Tasha Moore also giving testimony about this same man,Called Dr Itua Herbal Center.I was moved by the testimony and i contacted him by his Email.drituaherbalcenter@gmail.com We chatted and he send me a bottle of herbal medicine I drank it as he instructed me to.After drinking it he ask me to go for a test that how i ended my suffering life of Hiv patent,I'm cured and free of Arv Pills.I'm forever grateful to him Drituaherbalcenter.Here his contact Number +2348149277967...He assure me he can cure the following disease..Hiv,Cancer,Herpes Virus,Epilepsy, fibromyalgia ,ALS,Hepatitis,Copd,Parkinson disease.Genetic disease,Fibrodysplasia Ossificans Progressiva,Factor V Leiden Mutation ,Fatal Familial Insomnia ,Dupuytren's disease,Fibrodysplasia Ossificans Progressiva,Fluoroquinolone Toxicity Syndrome,Inflammatory bowel disease ,Huntington's disease ,Diabetes,Fibroid...

    Trả lờiXóa

  19. I was in trouble when my doctor told me that i have been diagnosed with
    herpes and i know my family will face a serious problem . when i am gone i
    lost hope and wept most of the time, but one day i was surfing the internet
    i saw Dr. omohan herbal home contact number online i called him and he
    guided me. i asked him for solutions and he started the remedy for my
    health thank God,now everything is fine i am cured by Dr. omohan herbal
    medicine am very thankful to Dr. omohan and very happy with my hobby and
    family email him on (dromohanherbalmedicine@gmail.com) call/whatsapp number +2348164816038

    He can as well cure the following disease;

    Herpes,
    Asthma,
    Cancer,
    HSV1, &
    HSV2,
    Hepatitis B,
    HIV/AID ETC.

    Trả lờiXóa
  20. I has suffered for Human papillamvirus HPV) for 2years, I was given some tablets at the hospital but I refused to take it, They said I have to be on it for life so I don't want take a drugs everyday for life. No point in taking medicine everyday when u won't get cure from it and I was advice to seek for natural herbal cure, after some time I found DR OLIHA is the most trustful herbalist that have herbs to cure wicked symptom's,I emailed DR OLIHA for 2weeks been his patient he cured my (HPV) with his herbal. I only used his natural herbs for two weeks it was 100% cure. I'm not (HPV) patient anymore. I'm happy about it i finally got cured out of this mess been in my body for 2years. I also recommend you if you're living with (HPV) or herpes symptoms i also want you to be free contact DR OLIHA with the email attach to my post {oliha.miraclemedicine@gmail.com} you call or whats app his number on +2349038382931

    Trả lờiXóa
  21. My life is beautiful thanks to you, Mein Helfer. Lord Jesus in my life as a candle light in the darkness. You showed me the meaning of faith with your words. I know that even when I cried all day thinking about how to recover, you were not sleeping, you were dear to me. I contacted the herbal center Dr Itua, who lived in West Africa. A friend of mine here in Hamburg is also from Africa. She told me about African herbs but I was nervous. I am very afraid when it comes to Africa because I heard many terrible things about them because of my Christianity. god for direction, take a bold step and get in touch with him in the email and then move to WhatsApp, he asked me if I can come for treatment or I want a delivery, I told him I wanted to know him I buy ticket in 2 ways to Africa To meet Dr. Itua, I went there and I was speechless from the people I saw there. Patent, sick people. Itua is a god sent to the world, I told my pastor about what I am doing, Pastor Bill Scheer. We have a real battle beautifully with Spirit and Flesh. Adoration that same night. He prayed for me and asked me to lead. I spent 2 weeks and 2 days in Africa at Dr Itua Herbal Home. After the treatment, he asked me to meet his nurse for the HIV test when I did it. It was negative, I asked my friend to take me to another nearby hospital when I arrived, it was negative. I was overwhite with the result, but happy inside of me. We went with Dr. Itua, I thank him but I explain that I do not have enough to show him my appreciation, that he understands my situation, but I promise that he will testify about his good work. Thank God for my dear friend, Emma, I know I could be reading this now, I want to thank you. And many thanks to Dr. Itua Herbal Center. He gave me his calendar that I put on my wall in my house. Dr. Itua can also cure the following diseases ... Cancer, HIV, Herpes, Hepatitis B, Inflammatory Liver, Diabetis, Bladder Cancer,Colorectal Cancer,Breast Cancer,Kidney Cancer,Leukemia,Lun,Fribroid,Parkinson's disease,Inflammatory bowel disease ,Fibromyalgia, recover your ex. You can contact him by email or whatsapp, @ .. drituaherbalcenter@gmail.com, phone number .. + 2348149277967 .. He is a good doctor, talk to him kindly. I'm sure he will also listen to you.
    Here is my Email contact...piresmis59@gmail.com.

    Trả lờiXóa
  22. CURED FROM HERPES VIRUS ...indeed DR OSE IS a God sent to cure HERPES
    DR OSE is the only Dr who could ever get Herpes cured with his healing medicine, i have tried almost everything but i couldn't find any solution on my disease, despite all these happening to me, i always spend a lot to buy drugs from hospital and taking some several medications but no relieve, until one day i was just browsing on the internet when i come across a great post of 'Morrison' who truly said that he was been diagnose with Herpes and was healed the nest week through the help of this great powerful healing doctor, so i quickly contacted him, and he ask me some few questions and he said a thing i will never forget that any one who contacted him is always getting his or her healing ,so i was amazed all the time i heard that from him,so he sent me the herbal medicine ,and after taking his medicine for the period of time he told me to, i noticed a very hug difference in my health,so i went to the hospital to give the final test to the disease and the doctor said i am HERPES NEGATIVE ,i am very amazed and happy about the healing DR OSE gave to me from the help of his ancient herbs But if you feel like contacting DR OSE at once you can email him now for your own healing too at :(dr.oseherbalspellhome@gmail.com).
    whatsApp /CALL +2348080488708

    Trả lờiXóa
  23. I has suffered for Human papillamvirus HPV) for 2years, I was given some tablets at the hospital but I refused to take it, They said I have to be on it for life so I don't want take a drugs everyday for life. No point in taking medicine everyday when u won't get cure from it and I was advice to seek for natural herbal cure, after some time I found DR OLIHA is the most trustful herbalist that have herbs to cure wicked symptom's,I emailed DR OLIHA for 2weeks been his patient he cured my (HPV) with his herbal. I only used his natural herbs for two weeks it was 100% cure. I'm not (HPV) patient anymore. I'm happy about it i finally got cured out of this mess been in my body for 2years. I also recommend you if you're living with (HPV) or herpes symptoms i also want you to be free contact DR OLIHA with the email attach to my post {oliha.miraclemedicine@gmail.com} you call or whats app his number on +2349038382931

    Trả lờiXóa
  24. I was suffering from HERPES Simplex Virus, i was totally depressed due to my predicament , until i meet Dr zozo the great Traditional healer who cured me. you can also contact him now on whatsapp +2348130970822.or via email:on drzozoherbalhome@gmail .com for more information.

    Trả lờiXóa
  25. MY HERPES DISEASE WAS CURED BY PROPHET Jennifer, WITH HIS HERBAL HEALING TREATMENT (Dr.airehome@gmail.com ).(+2347036740271
    DR Aire is the only Dr who could ever
    get my HERPES cured with his healing spell, I have tried almost
    everything but I couldn't find any solution on my herpes infection, despite all
    these happening to me, I always spend a lot to buy drugs from
    hospital and taking some several medications but no relieve, until one
    day I was just browsing on the internet when I come across a great
    post of Osas Ruth! who truly said that she was been diagnose with herpes
    and was healed that very week through the help of these great powerful
    healing doctor, sometime I really wonder why people called him
    Papa Aire, I never knew it was all because of the great and perfect
    work that he has been doing that is causing all this. so I quickly
    contacted him, and he ask me some few questions and he said a thing I
    will never forget that anyone who contacted him is! always getting his
    or her healing in just 8 hours after doing all he ask me , so I was
    amazed all the time I heard that from him, so I did all things only to
    see that at the very day which he said I will be healed, all the
    strength that has left me before rush back and I becomes very strong
    and healthy, this infection almost kills took my life , so I
    went to hospital to give the final test for my herpes infection and the doctor
    said I'm alright now , I am very amazed and happy about the healing
    Dr Aire gave to me and this my mail if you need more information
    drairehome@gmail.com and he also cure all manner of diseases

    Trả lờiXóa
  26. I want to share a testimony of how Dr.Omohan herbal mixture cream saves me from shame and disgrace, my penis was a big problem to me as the size was really so embarrassing,and i was also having weak erection problem. I can't make love to my wife and my penis was just too small a full grown man like me having 4 inches penis and to worsen it i don't last in sex i cant even last two minutes it was really a thing of shame to me. My wife was really tired of me because my sex life was very poor,she never enjoyed sex,i was always thinking and searching for solutions everywhere until when i saw a testimony of how Dr.omohan herbal mixture cream have been helping people regarding their sex life, so i decided to give him a try and to my greatest surprise in less than one week of taking the herbs my penis grow to 8 inches i couldn't believe my eyes and as i speak now my penis is now 8 inches and i do not have week erection again. I can make love to my wife longer in bed. And my marriage is now stable,my wife now enjoy me very well in bed. can contact him dromohanherbalmedicine@gmail.com {) or call or what-apps him through +2348164816038. . .he also specialize on the following things

    BREAST ENLARGEMENT
    BREAST LIFT & REDUCTION
    PENILE/PENIS ENLARGEMENT
    GENERAL BODY SLIMMING
    HIPS & THIGH REDUCTION
    REGAIN VIRGINITY BACK
    Thanks for the Enlarging my penis sir, you indeed save my marriage...I am really grateful sir,

    Trả lờiXóa
  27. Good news My people. I want to thank Dr. Kelvin Herpes. Medicine is a good herbal medicine for the HERPES virus. I was diagnosed with the HERPES virus last month, and was looking for a solution to cure. Fortunately, I saw a testimony about how Dr.Kelvin CURE HERPES VIRUS I decided to contact Dr. Kelvin I contacted him He prepared a portion of herbal medicine and sent it to me, I started herbal medicine for my health. He gave me step by step instructions on how to apply it, when I applied it as instructed, I was cured of this deadly herpes virus within 2 weeks, now I am negative Kelvin . My brother and sister I do not know that there are so many people who have the same herpes virus, please Dr. Kelvin to help him too, and help me to thank Dr. Kelvin for healing me, I am cured by Dr. Kelvin Medicine, his email Contact: drkelvinherbalcure@gmail.com Cell or Whatsapp Number +2348154637647. Dr Kelvin also has the cure for, HIV / AIDS, psoriasis, cancer,HBP, HPV may God bless you sir for your good works.

    Trả lờiXóa
  28. This is to testify to the general public about a great herbal doctor who saved my wife from Fibroid, His name is Dr. Uduehi. My wife suffered fibroid with pelvic pain and heavy menstrual bleeding for 6 years and with miscarriages. I couldn't bear the pain and sufferings my wife was passing through so I have to confide in a friend about our predicaments, she gave me doctor Uduehi's contact and I did contacted him and after she took his medication she became cured and sound. The fibroid gone, no pelvic pain and menstrual bleeding anymore. You can reach him through: uduehiherbalcare@gmail.com phone/WhatsaPP: +2347084878384

    Trả lờiXóa
  29. HOW I GOT CURED FROM HPV WARTS VIRUS
    Dr.Omohan herbal medicine is a good remedy for HPV WARTS , I was browsing through the Internet searching for remedy on HPV WARTS cure and i saw comment of people talking about how Dr.Omohan cure them from HPV WARTS, I decided to contact, I contacted him and he guided me. I asked him for solutions and he started the remedies for my health. Thank God, now everything is fine, I’m cured by Dr.Omohan herbal medicine, I’m very thankful to Dr.Omohan, reach him on dromohanherbalmedicine@gmail.com WHATSAPP HIM VIA +2348164816038.

    Trả lờiXóa
  30. HOW I GOT CURED FROM HPV WARTS VIRUS
    Dr.Omohan herbal medicine is a good remedy for HPV WARTS , I was browsing through the Internet searching for remedy on HPV WARTS cure and i saw comment of people talking about how Dr.Omohan cure them from HPV WARTS, I decided to contact, I contacted him and he guided me. I asked him for solutions and he started the remedies for my health. Thank God, now everything is fine, I’m cured by Dr.Omohan herbal medicine, I’m very thankful to Dr.Omohan, reach him on dromohanherbalmedicine@gmail.com WHATSAPP HIM VIA +2348164816038.

    Trả lờiXóa
  31. I was suffering from Warts Simplex Virus, i was totally depressed due to my predicament , until i meet Dr Nana the great Traditional healer who cured me. you can also contact him now on whatsapp +2347014784614.or via email:on drnanaherbalsolutionhome@gmail .com for more information.

    Trả lờiXóa
  32. HOW I GOT CURED FROM GENITAL HERPES COMPLECTED.

    I know there is no cure for genital herpes but take a moment and read my testimony.
    My health was horrible before I decided to try the Protocol Of taking Dr HENRY herbal mixture. I felt there was no hope for my health and I was doubtful to try the Protocol thinking it wouldn’t work because I have visited so many hospital but same result. However, I was convinced by my friend to try the herbal medicine because I wanted to get rid of herpes. The herbal mixture that was given to me was really quick and easy to take, and since I have be taking it for less than 3 days I have less outbreak. But within one week i was fully cured from herpes simple. We herbal medicine really work and I will like to share this great herb doctor contact with you all email him henryazakaherbalhome@gmail.com or whatsapp +2348107397241. Pls try and help yourself out of herpes completely today. ACCORDING TO HIM HE ALSO CURE ALL TYPE OF ILLNESS LIKE
    DIABETES
    ALL TYPE HERPES
    HIV
    FIBROID
    HPV....

    Trả lờiXóa
  33. I’m indeed very happy for the great help that Dr.Afrid rendered to me, I am here to give my testimony about a doctor who helped me in my life. I and my husband was infected with HERPES SIMPLEX VIRUS last 4 years ago, we went to many hospitals for cure but there was no solution, on till one faithful day , we saw a blog whereby Dr. Afrid cured a woman who also had herpes affection,we (Me and My HUSBAND) decided to contact him which we did, he asked us to buy some items, unfailingly we sent him the money he will need in buying the items required , He caste the spell and sent me some herbs. He asked me to go for check-up after 7 days of casting the spell, Luckily for me we were tested herpes negative, now I believe all these Testimonies about him on the internet, he is truly a great man, if you are going through the same problem and you need help you can contact the great Herbalist (drafridherbalhome@gmail.com) or you can call him or message him on +17734535649.

    Trả lờiXóa
  34. God bless Dr Omohan for his marvelous work in my life, I was diagnosed of HERPES SIMPLEX VIRUS since 2010 and I was taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched about some possible cure for HERPES i saw a comment about Dr Omohan, how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine within 3days. I took the medicine as prescribed by him and 2weeks later i was cured from HERPES contact him via email dromohanherbalmedicine@gmail.com once again thanks to you Dr . omohan cure the flowing virus, contact his email or add him on whatsapp +2348164816038)

    cancer cure
    diabetes cure
    ringing ear
    herpes cure
    warts cure
    HPV cure
    HIV cure
    get your ex back
    pregnancy herbal medicine
    prostate enlargement
    Hepatitis

    Trả lờiXóa
  35. God bless GREAT Dr irabor for his marvelous work in my life, I was diagnosed of HPV since 2015 and I was taking my medications, I wasn't satisfied and I needed to get the HPV out of my blood, I searched about some possible cure for HPV and I saw a comment about GREAT Dr irabor , how he cured HPV with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS SPEED POST. I took the medicine as prescribed by him and 14 days later I was cured from HPV. GREAT Dr irabor , truly you are great. Do you need his help also? Why don't you contact him through this Email:dr.iraborherlcenter@gmail.com
    GREAT Dr IRABOR CAN AS WELL CURE THE FOLLOWING DISEASES:-
    1. HIV/AIDS
    2. HSV
    3 LUPUS
    4. ALS
    5. HEPATITIS B
    6. DIABETES
    7. HUMAN PAPILOMA VIRUS DISEASE(HPV)
    8. ALZHEIMER
    Whstsap him on +2348158847469

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  36. Hello everybody, I am very happy that i and my husband are cured of (HERPES SIMPLEX VIRUS) with the herbal medicine of Dr Omonzukpia, i have been suffering from this disease for the past 3 years without solution until i came across the email of this great doctors who have cure so many people with his herbal medicine, i also choose to give him a chance to help me and my husband, he told me what to do and i kindly did it, and he gave us his herbal medicine and direct me on how to use it, i also follows his instruction for use and he ask us to go for a check up after 1 week and which i did, to my greatest surprise our result came out as negative, we are really happy that there is someone like this great Dr Omonzukpia who is ready to help anytime any day. to all the readers and viewers that is doubting this testimony stop doubting it and contact this Great Dr Omonzukpia and see if he will not actually help you. i am not a stupid woman that i will come out to the public and start saying what someone have not done for me. contact him on his Email: dromonzukpiaherbalhome@gmail.com
    Website: dromonzokpiaherbalhome.wordpress.com or you can call or whatsapp him on +2348083221034

    Trả lờiXóa
  37. I was diagnose with genital warts since 2012 i have be taking lot treatment and all i got is outbreak. in 2015 I gave up the treatment because I can't continues wasting time and money on treatment at the end it will not cure me. about 6 weeks ago i did natural research online I had So many people talking good about natural remedy, after the research i was recommended to Dr onokun, And I wrote to him through his email and told him my problem after some conversations with him he gave me natural treatment after 1 week Dr onokun treated me i got cured permanently. and i went to see my doc he confirmed that the diseases has gone out from my body. every patients should know there is 100% natural hpv cure. contact Dr onokun his email address: dronokunherbalcure@gmail.com

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  38. I can’t believe this is really true I never believe there is cure to this hsv 2 because all the hospital have told me there is no cure to it, few months ago I saw this man email DR OLIHA on internet from a testimony share by someone who he help with his herbal cure I contact his email and ask for his help also, that is how he inform me about the cure process and this man sent me a herbal medicine which I took according to the way he instructed for 2 week I can’t believe when I go for test my result come out negative i am so happy to share this to the world there is real cure to herpes you can also contact DR.OLIHA through his email now {oliha.miraclemedicine@gmail.com} and also WhatsApp him +2349038382931. .....

    Trả lờiXóa
  39. I was diagnose with genital warts since 2012 i have be taking lot treatment and all i got is outbreak. in 2015 I gave up the treatment because I can't continues wasting time and money on treatment at the end it will not cure me. about 6 weeks ago i did natural research online I had So many people talking good about natural remedy, after the research i was recommended to Dr onokun, And I wrote to him through his email and told him my problem after some conversations with him he gave me natural treatment after 1 week Dr onokun treated me i got cured permanently. and i went to see my doc he confirmed that the diseases has gone out from my body. every patients should know there is 100% natural hpv cure. contact Dr onokun his email address: dronokunherbalcure@gmail.com

    Trả lờiXóa


  40. Am jeremiah, I am testifying about a great hebal man that cured my wife of hepatitis B and liver cirhosis. his name is Dr oniha. My wife was diagnose of hepatities two years ago, i almost spent all i had then, until i saw dr oniha recommendation online, and i call him, then he told me how to get the herb. You can call him on +2347089275769 or email him at dronihaspell@yahoo.com

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  41. I was despondent because i had a very small penis, about 2.5 inches soft and 4 inches hard not nice enough to satisfy a woman, i have been in so many relationship, but cut off because of my situation, i have used so many product which doctors prescribe for me, but none could offer me the help i searched for. i saw some few comments on the INTERNET about this specialist called Dr movo and decided to contact him on his email: {drmovo.supernaturalherbalmedic@gmail.com} so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal pills for Penis Enlargement, Within 3 week of it, i began to feel the enlargement of my penis, " and now it just 4 weeks of using his products my penis is about 9 inches longer, and i had to settle out with my Ex girlfriend JOY, i was surprised when she said that she is satisfied with my sex and i have got a large penis. Am so happy, thanks to Dr movo I also learn that Dr movo also help with Breast Enlargement Hips and Bums Enlargement etc.. If you are in any situation with a little Penis, weak ejaculation, small breast_hips_bums do get to Dr movo now for help on his email:{drmovo.supernaturalherbalmedic@gmail.com} or whatsapp +2347061865209.

    Trả lờiXóa
  42. Hello, i just want to pass a brief information to you all here about the cure for HPV vIRUS, i have been sick with this Virus for the past some Years now, i did all i could to be cured , i went to different hospitals but no cure was found so to make it shot, a friend of mine (Alisha) visited me and told me about a herbal Dr called Dr AZIBA who cured her mum from diabetes just some weeks ago and assured me that the herbal Dr is well known and he will send me his medicine and that will be the end of my virus after i must have use it according to his instructions, i had no choice again so i contacted the Dr and explained to him my problems, so he actually sent me the medicine here and which i used according to his instruction and today i am totally cured from HPV/WART, I went for text and ,my home Dr comfimed to me that am texted Negative and that i am strong and healthy, i say a very big thanks to Dr Aziba for his help and i will also write down his contacts so you can apply for your cure or any other disease or virus you may be having popularly like....
    HEPATITIS A,B AND C
    DIABETICS 1/2
    CANCER
    ALS,HPV 1/2
    HIV AIDS
    BODY REDUCTION AND
    Enlargement
    FIBROD
    CANCER
    PREGNANCY
    Relationship issues etc. all you just have to do is to contact Dr Aziba via
    Email: PRIESTAZIBASOLUTIONCENTER@GMAIL.COM
    WhatsApp: +234810036828


    Trả lờiXóa
  43. I came across a testimony on you- tube about a lady that was cured from Genital herpes by Dr. Ahmed Usman Herbal Medicine. I showed the testimony to my fiancee who discouraged me for contacting the doctor. But because I was so desperate to cure mine I contacted Dr. Ahmed with the email I found on the testimony, which he replied minutes later and asked me the type of HSV I have. After much discussion he decided to call me so that I won't feel he is a scammer. He sent the Herbal Medicine to my country which I took for two weeks with the doctor prescription. The sores in my lip was gone and I felt different. So I went for a check-up and my result came out negative. My fiancee was surprised and he ordered for his Medicine too from Dr. Ahmed which he is taking recently. Please don't let anyone discouraged you. No harm in trying. This is Doctor Ahmed Usman email address; drahmedusman5104@gmail.com or Whatsapp +2348064460510. He has cure for any type of infections.

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  44. OMG i am here to tell you all how i was cured from Hepatitis B by
    dr Adigba with his herbal medicine i once had the problem of
    Hepatitis B which affected my work for years i have been using
    different medication but there was no solution,i search the net and
    i found the contact of Dr Adigba who help me with his product on
    curing Hepatitis B problem and other deadly diseases, he also
    assured me that it is a permanent cure,so i work with him
    as he ask
    and i took the medication for just 1 weeks and i was back
    to normal.
    for two weeks now i have been doing fine.I give all thanks
    to Dr
    Adigba for helping me out of such problem now am the
    happiest
    person on earth for seeing myself doing better again.you
    can also
    contact him on email drAdigba@gmail. com whatsapp him
    on +2348077875210
    dr adigba cure the flowing virus
    1 cancer cure
    2 diabetes cureringing ear
    3 ringing earwarts cure
    4 herpes cure
    5 warts cure
    6 HPV cure
    7 Jaundice
    8 pregnancy herbal medicine
    9 prostate enlargement
    10 Hepatitis B and many more  

    Trả lờiXóa
  45. i already gave up on ever getting cured of HSV2 because i have try many treatment none of them work out for me i have go to different hospital they always tell me same thing there is no cure for herpes when i came across a post about Dr ohunyom, in the net from a lady called Angela i contacted him and he reassured me with him herbal medicine which i took according to the way he instructed, that how i was cured. I doubted at first because i have been to a whole lot of reputable doctors, tried a lot of medicines but none was able to cure me. so i decided to listen to him and he commenced treatment, and under two weeks i was totally fee from #Herpes. i want to say a very big thank you to DR ohunyom for what he has done in my life. feel free to leave him a message on email drohunyom@gmail.com and also WhatsApp him +2349060579973..
    He can still be able to help you with this herbs medicine:
    1...ALS CURE/DIABETES CURE/EPILESY/HPV CURE/LUPUS/HEPATITIS/CANCER/GOUT      

    Trả lờiXóa
  46. it so amazing on everyone who contacted hpv to know about this 100% natural treatment which i also used to cure hpv out of my body. i'm free from this virus i found about the cure online from an ex hpv patient who also got rid of hpv with same natural treatment. everyone suffering from this virus should also inquire this cure. contact the traditional healer DR MOSES. through his  email dr.mosesherbalisthome@gmail.com  or what's app number +2348109374702...........

    Trả lờiXóa
  47. Joy and happiness is all i see around ever since i came in contact with this great man. i complained bitterly to him about me having herpes only for him to tell me it’s a minor stuff. He told me he has cured thousands of people but i did not believe until he sent me the herbal medicine and i took it as instructed by this great man, only to go to the hospital after two weeks for another test and i was confirmed negative. For the first time in four years i was getting that result. i want to use this medium to thank this great man. His name is Dr aziegbe, i came in contact with his email through a friend in UK and ever since then my live has been full with laughter and great peace of mind. i urge you all with herpes or HSV to contact him if you willing to give him a chance. you can contact him through this email DRAZIEGBE1SPELLHOME@GMAIL .COM or you can also WhatsApp him +2349035465208
    He also cured my friend with HIV and ever since then i strongly believe he can do all things. Don't be deceived thinking he does not work, i believe if you can get in contact with this man all your troubles will be over. i have done my part in spreading the good news. Contact him through his email and you will be the next to testify of his great work.

    Trả lờiXóa
  48. I believed God has sent dr ododo to help people out from this horrible virus. i was diagnosis with herpes for 3 years, few months ago a friend introduced me to dr ododo and i only took his natural treatment for a week & 3 days, and i totally got cured with his herbal treatment. if you are suffering from genital herpes, you don't have to be roaming round dr ododo email is been attached to contact him.{drododoherbalhome1@gmail.com }or whats-app {+2348079954368} GOOD LUCK  

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  49. God bless Dr ODUWA for his marvelous work in my life, I was diagnosed of HPV SIMPLEX VIRUS since 2010 and I was taking my medications, I wasn't satisfied i needed to get the HIV out of my system, I searched about some possible cure for HPV i saw a comment about Dr ODUWA, how he cured HPV with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine within 3days. I took the medicine as prescribed by him and 2weeks later i was cured from HPV contact him via email dr.oduwaspellhome@gmail.com. once again thanks to you DR . ODUWA cure the flowing virus, contact his email or add him on whatsapp +2348070685053)

    cancer cure
    diabetes cure
    ringing ear
    herpes cure
    warts cure
    HPV cure
    HIV cure
    get your ex back
    pregnancy herbal medicine
    prostate enlargement
    Hepatitis

    Trả lờiXóa
  50. Dr. oduwa has really made me so much believe in him by getting me cured with his herbal treatment. I really appreciate you Dr. oduwa for bringing back happiness to my life again. thank you so much, friends join me to thank him for what he has actually done for me I pray to you all for a good life and good health, and most especially to you Dr. oduwa THANKS.
    I have been suffering from (HPV SIMPLEX VIRUS) disease for the past four years and had constant pain, especially in my knees. During the first year, I had faith in God that I would be healed someday. This disease started circulating all over my body and i have been taking treatment from my doctor, few months ago i came on search on the internet if i could get any information concerning the cure of this disease, on my search i saw a testimony of someone who has been healed from (HPV SIMPLEX VIRUS) by this Man Dr. oduwa and she drop the email address of this man and advise we should contact him for any sickness that he would be of help, so I wrote to Dr. oduwa telling him about my (HPV Virus) well after all the procedures and remedy given to me by this man a few weeks later i started experiencing changes all over me. I am nowhere to testify that i am no longer a herpes patient, I have experienced a total transformation in my life, and for all HPV patients get your herbal medicine to cure your sickness. And there has been rapid improvement in my health, I no longer feel pains and I wake up each morning feeling revived. So friends my advice is if you have such sickness or any other at all, you can contact him. (dr.oduwaspellhome@gmail.com) Website: https://myoduwa2blogaddress.blogspot.com or whatsapp +2348070685053
    CANCER
    EPILEPSY.
    GENPILENCIN.
    HIV AIDS.
    DIABETICS
    STROKE.
    EXPANDS OF PENIS BREAST
    H.P.V TYPE 1 TYPE 2 TYPE 3 AND TYPE 4. TYPE 5.
    HUMAN PAPILLOMAVIRUS.
    HERPES.
    SYPHILIS.
    HEPATITIS A B and C.

    Trả lờiXóa
  51. I have been suffering from (HERPES SIMPLEX VIRUS) disease for the past four years and had constant pain, especially in my knees. During the first year, I had faith in God that I would be healed someday. This disease started circulating all over my body and i have been taking treatment from my doctor, few months ago i came on search on the internet if i could get any information concerning the cure of this disease, on my search i saw a testimony of someone who has been healed from (HERPES SIMPLEX VIRUS) by this Man Dr. ODUWA and she drop the email address of this man and advise we should contact him for any sickness that he would be of help, so I wrote to Dr ODUWA telling him about my (HERPES Virus) well after all the procedures and remedy given to me by this man a few weeks later i started experiencing changes all over me. I am nowhere to testify that i am no longer a herpes patient, I have experienced a total transformation in my life, for all herpes patients get your herbal medicine to cure your sickness. And there has been rapid improvement in my health, I no longer feel pains and I wake up each morning feeling revived. So friends my advise is if you have such sickness or any other at all, you can contact him. (dr.oduwaspellhome@gmail.com) or whatsapp number +2348070685053
    CANCER
    EPILEPSY.
    GENPILENCIN.
    HIV AIDS.
    DIABETICS
    STROKE.
    EXPANDS OF PENIS BREAST
    H.P.V TYPE 1 TYPE 2 TYPE 3 AND TYPE 4. TYPE 5.
    HUMAN PAPILLOMAVIRUS.
    HERPES.
    SYPHILIS.
    HEPATITIS A B and C.

    Trả lờiXóa
  52. I'm 61 years old, I contracted hpv in 2011' I has be taking lot treatment for it and embarrassedsome months ago the wart stated coming out seriously, I used lot recommendation because there was lot warts around my anus and was so . but today I'm totally happy I got the virus eliminated by using natural treatment from Dr Onokun herbal center after his treatment I got cured. all the warts went away' seriously believed Dr Onokun he have the cure for human papillomavirus because he has eliminated hpv been in my body since 2011, Dr Onokun make it possible for me. Here is Dr Onokun email to reach him: Dronokunherbalcure@gmail.com  he is welled capable of curing terrible diseases.  

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  53. My life is full of Joy and happiness now , i never believe that this will work, i have spend a lot money getting drugs from the hospital to keep me and my son healthy, it got to a point that i was waiting for a death to come because i was broke, one day i hard about this great man called Dr Ehiaguna who is well know for Herpes, HIV, and Cancer cure, i decided to email him I didn’t believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent it to him, and he prepared a herbal medicinAe (CURE) and, he gave my details to the Courier Office. they told me that 4days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of the two weeks, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me Herpes simplex virus negative, and my son an i thought it was a joking, i went to other hospital and was also negative, thank you for saving our life’s, I promise I will always testify of your good works. if you are herpes simplex virus patient, contact him and I am sure you will get cured, contact him via:drehiaguna@gmail.com WHATSAPP: +2348073908953 and He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

    Trả lờiXóa
  54. Thanks for sharing such a valuable information it was very helpful
    Types of Warts and Best Treatment Options

    Trả lờiXóa
  55. HELLO EVERYONE.. FEW MUNINETS TO REDY THIS INFOR ON HERPES CURE 2018..
    2017 MY MOTHER WAS DIAGNOSED OF HERPES/ KNOWN AS GENITAL WARTS ,I SPENT A LOT OF MONEY ON HER MEDICATION TILL A POINT I EVEN LOST HOPE,BECAUSE MY MOTHER WAS GRADUALLY DYING AND LOST HER MEMORY TOO, I WAS SO DESPERATE TO GET MY MOTHER BACK TO NORMAL, ONE DAY MY UNCLE WHO LIVES IN LONDON UNITED KINGDOM TOLD ME ABOUT DR OLIHA ,WHO HELPED HIM GET RID OF HERPES /GENITAL WART WITH HERBAL MEDICINE AND HIS HERBAL SOAP ,I WAS SO SHOCKED WHEN HE TOLD ME ABOUT THIS ,ALTHOUGH I NEVER BELIEVE IN HERB BUT, I KEEP TO BELIEVE BECAUSE MY UNCLE CAN'T TELL ME LIES WHEN IT COMES TO HEALTH CONDITION I CONTACTED DR OLIHA VIA HIS EMAIL; OLIHA.MIRACLEMEDICINE@GMAIL.COM , YOU CAN TALK TO HIM VIA CALL OR WHATSAPP MESSENGER ON +2349038382931 , HE REPLIED AND ASK ME TO SEND MY HOME ADDRESS AND MY MOTHER'S DETAIL AND THEN I PURCHASED THE HERBAL MEDICINE,SENT ME THE HERBAL MEDICINE THROUGH COURIER SERVICE, WHEN I RECEIVED THIS HERBAL MEDICINE USED IT FOR 2 WEEKS, AND 4 DAYS OF USAGE THE WARTS FELL OFF, MY MOTHER I NOW TOTALLY CURED AND MY MOTHER IS LIVING FREE AND HAPPY AGAIN. YOU CAN TALK TO DR VIA HIS MOBILE NUMBER OR WHATS APP HIM ON +2349038382931 or Facebook page https://www.facebook.com/drolihamiraclemedicine/  ALL THANKS TO DOCTOR DR OLIHA  

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  56. This is my testimony about the marvelous work Dr Osebor did for me. My husband abandon me and the kids and he went to stay with another woman who he just met. And the woman did spell on him so that he will never have nothing to do with me and my kids for that, my self and the kids has been suffering and it has been hell of a struggle, but I decide to do all means to make sure that my family come together as it use to, then I went online there I saw so many good talk about this spell caster called Dr Osebor So I had to contact him and explain my problem to him and in just 48hours as Dr Osebor has promised, my husband came home and his behavior was back to the man i got married to. I can’t thank the spell caster enough for what he did for me, i am so grateful and i will never stop to publish his name on the internet for the good work he has done for me, once again thanks Dr Osebor
    email: ( oseborwinbacktemple@gmail.com ) .. You can contact him on WhatsApp +2348073245515

    Trả lờiXóa
  57. All thanks to Dr Alli for curing my herpes virus/hpv with his herbal medicine, i do not have much to say but with all my life i will forever be grateful to him and God Almighty for using Dr Alli to reach me when i thought it was all over, today i am happy with my life again after the medical doctor have confirmed my HERPES SIMPLEX VIRUS / HPV of 5 is gone,i have never in my life believed that HERPES SIMPLEX VIRUS could be cured by herbal medicine. so i want to use this means to reach other persons who have this disease by testifying the power of Dr Alli that all hope is not lost yet, try and contact him by any means for any kind of disease with his email: ( Allispellhelp1@gmail.com ) or his whatsapp number +2348100772528 and get your healing

    Trả lờiXóa
  58. Getting rib of Herpes virus wasn't easy, I came across Dr voodoo on how he
    has cured so many people from herpes and other illness so I decided to give
    him a try, now am permanently cured using the natural herbs medication and
    cleansing supplement sent by Dr voodoo no more herpes, contact Dr voodoo
    WhatsApp number +2348140120719 also e-mail him at:
    voodoospelltemple66@gmail.com

    Trả lờiXóa
  59. At the Pittodrie Podiatry Practice we understand the importance of finding the right team of professionals for you, your family and your staff.The Pittodrie Podiatry Practice in Aberdeen provides Best Verruca Treatment in Aberdeen with fully qualified Podiatrists.

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  60. Cure herbals Permanent Hair Removal Cream is one of the effective herbal formulas that can be use on all type of skin like sensitive and normal.

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